Table of Handouts for ENAS 915

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--Evan 14:05, 14 March 2013 (EDT)--Evan 14:05, 14 March 2013 (EDT)Table of Handouts for ENAS 915 --- Tracer Kinetics and Modeling

Spring semester 2013

Yale

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Author
Handout Title Journal Date Comment   Class Time   Room Location
Class Author Chapter/ Paper etc
Source Publisher/Journal Year Notes Class time
Room








TAC N207

Kevles chapter 9 "Naked to the Bone: Medical Imaging in the 20th Century" Basic Books 1998


TAC N207

Levi The development of the tracer method "George de Hevesy. Life and Work" Rodos
Homework #1


Tues, Jan 22 Axel methods using blood pool tracer chap 11 Diffusion-and-perfusion-Magnetic-Resnoance-Imaging (Le Bihan, ed) Raven Press 1995
5:00pm
TAC N207

Cobelli, Foster, and Toffolo Fundamentals of Tracer Kinetics Tracer Kinetics in Biomedical Research Kluwer Academic / Plenum Publishers 2000


Thurs, Jan 24
Kennan and Jager
T2- and T∗ 2 -w DCE-MRI: Blood Perfusion and Volume Estimation using Bolus Tracking
Quantitative MRI of the Brain (Tofts, ed)
Wiley
2003
see pgs 365-377 and figures of clinical applications: 11.10-11.21
5:15pm
TAC N207

Calamante et al Measuring Cerebral Blood Flow Using Magnetic Resonance Imaging Techniques
Journal of Cereb Blood Flow 1999 see pgs 701-705 and figures of applications


Tues, Jan 29
Chen et al
Akella et al
Wuerfel et al
Nabors et al
Ma et al


Automatic determination ofAIF for DCE MRI in Tumor Assessment
Assessment of Brain Tumor Angiogenesis Inhibitors Using Perfusion Magnetic Resonance Imaging: Quality and Analysis Results of a Phase I Trial
Changes in cerebral perfusion precede plaque formation in multiple sclerosis: a longitudinal perfusion MRI study
Phase I and Correlative Biology Study of Cilengitide in Patients With Recurrent Malignant Glioma
Perfusion MRI before and after acetazolamide administration for assessment of cerebrovascular reserve capacity in patients with symptomatic internal carotid artery (ICA) occlusion: comparison with 99mTc-ECD SPECT



MICCAI
Journal of Magnetic Resonance Imaging
Brain
Journal of Clinical Oncology
Neuroradiology


2008
2004
2004
2007
2007


required reading for Homework #2
optional
optional
optional
optional


5:00pm
TAC N207




 




Thurs, Jan 31

  N O     C L A S S

 








 





Riggs chap 7 - Transfer of substances between biological compartments. Simple diffusion
The Mathematical Approach to Physiological Problems MIT Press 1963 Notes


Riggs chap 8 - Transfer of substances between biological compartments. General kinetics The Mathematical Approach to Physiological Problems MIT Press 1963 Notes





Journal




Tues Feb 5

Evan sick






Thurs Feb7

Evan sick






Tues Feb12

Nemo snow















Tues Feb 14
Kety and Schmidt
THE NITROUS OXIDE METHOD FOR THE QUANTITATIVE DETERMINATION OF CEREBRAL BLOOD FLOW IN MAN: THEORY, PROCEDURE AND NORMAL VALUES

J Clnical Investigation
1948
Homework #3



Kety
Regional Cerebral Blod Flow: Estimation by means of nonmetabolized diffusible tracers - an overview

Seminars in Nucl Med
1985




Dumke and Schmidt
Quantitative Measurements of Cerebral Blood Flow in the Macaque Monkey

Amer. J. Physiol.
1942
Supplemental


Soskin et al
The Influence of Epinephrine Upon the Exchange of Sugar Between Blood and Muscle

Amer. J. Physiol.
1933
Supplemental










Thurs Feb 28
Krogh
THE NUMBER AND DISTRIBUTION OF CAPILLARIES IN MUSCLES WITH CALCULATIONS OF THE OXYGEN PRESSURE HEAD NECESSARY FOR SUPPLYING THE TISSUE.

J Physiology
1919




Crone
The Permeability of Capillaries in Various Organs
as Determined by Use of the (Indicator Diffusion’ Method


Acta Physiol Scand
1963












March 7
Abramowitz and Stegun
Table of Laplace Transforms

see pages 1020-1022

(navigate the book with the links to pages in the left column)



Homework #4



Sokoloff
Excerpt from Sokoloff chapter in Phelps















Tuesday, April 2
Godfrey
Chapter 1: Introduction to Compartmental Modeling

Compartmental Models and Their Application
1983
Homework #5



Godfrey
Chapter 2: The Dynamics of Linear, Time-invariant Systems

Compartmental Models and Their Application
1983



Thursday, April 11
Patlak et al.
Graphical Evaluations of Blood-to-Brain Transfer Constants from Multiple-Time Uptake Data

Journal of Cerebral Blood Flow and Metabolism
1983




Patlak et al.
Graphical Evaluation of Blood-to-Brain Transfer Constants from Multiple-Time Uptake Data. Generalizations

Journal of Cerebral Blood Flow and Metabolism
1985




Sokoloff et al.
The 14C-deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat

Journal of Neurochemistry
1977
FDG












Carson et al Comparison of Bolus and Infusion Methods for Receptor Quantitation: Application to 18-F-Cyclofoxy and Positron Emission Tomography JCBF 1993 look at the appendices. A: when is graphical analysis linear, B: How to calculate response to Bolus + Infusion



Logan et al. Graphical Analysis of Reversible Radioligand Binding from Time-Activity Measurements Applied to N-c -methyl-( -)-Cocaine PET Studies in Human Subjects JCBF 1990




Logan A review of graphical methods for tracer studies and strategies to reduce bias Nuc med Biol 2003




Slifstein and Laruelle Effects of Statistical Noise on Graphic Analysis ofPET Neuroreceptor Studies JNM 2000
Homework 6 - final project










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