Class Period that covers the information
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Author
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Handout
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Title
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Journal
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Date
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Comment
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Class Time
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Room Location
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| Class
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Author
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Chapter/ Paper etc
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Source
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Publisher/Journal
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Year
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Notes
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Class time
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Room
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TAC N207
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Kevles
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chapter 9
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"Naked to the Bone: Medical Imaging in the 20th Century"
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Basic Books
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1998
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TAC N207
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Levi
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The development of the tracer method
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"George de Hevesy. Life and Work"
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Rodos
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Homework #1
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| Tues, Jan 22
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Axel
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methods using blood pool tracer chap 11
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Diffusion-and-perfusion-Magnetic-Resnoance-Imaging (Le Bihan, ed)
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Raven Press
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1995
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5:00pm
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TAC N207
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Cobelli, Foster, and Toffolo
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Fundamentals of Tracer Kinetics
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Tracer Kinetics in Biomedical Research
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Kluwer Academic / Plenum Publishers
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2000
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Thurs, Jan 24
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Kennan and Jager
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T2- and T∗ 2 -w DCE-MRI: Blood Perfusion and Volume Estimation using Bolus Tracking
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Quantitative MRI of the Brain (Tofts, ed)
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Wiley
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2003
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see pgs 365-377 and figures of clinical applications: 11.10-11.21
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5:15pm
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TAC N207
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Calamante et al
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Measuring Cerebral Blood Flow Using Magnetic Resonance Imaging Techniques
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Journal of Cereb Blood Flow
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1999
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see pgs 701-705 and figures of applications
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Tues, Jan 29
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| Chen et al
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| Akella et al
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| Wuerfel et al
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| Nabors et al
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| Ma et al
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| MICCAI
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| Journal of Magnetic Resonance Imaging
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| Brain
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| Journal of Clinical Oncology
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| Neuroradiology
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| required reading for Homework #2
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| optional
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| optional
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| optional
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| optional
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5:00pm
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TAC N207
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Thurs, Jan 31
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N O C L A S S
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Riggs
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chap 7 - Transfer of substances between biological compartments. Simple diffusion
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The Mathematical Approach to Physiological Problems
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MIT Press
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1963
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Notes
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Riggs
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chap 8 - Transfer of substances between biological compartments. General kinetics
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The Mathematical Approach to Physiological Problems
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MIT Press
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1963
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Notes
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Journal
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Tues Feb 5
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Evan sick
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Thurs Feb7
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Evan sick
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Tues Feb12
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Nemo snow
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Tues Feb 14
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Kety and Schmidt
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THE NITROUS OXIDE METHOD FOR THE QUANTITATIVE DETERMINATION OF CEREBRAL BLOOD FLOW IN MAN: THEORY, PROCEDURE AND NORMAL VALUES
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J Clnical Investigation
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1948
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Homework #3
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Kety
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Regional Cerebral Blod Flow: Estimation by means of nonmetabolized diffusible tracers - an overview
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Seminars in Nucl Med
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1985
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Dumke and Schmidt
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Quantitative Measurements of Cerebral Blood Flow in the Macaque Monkey
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Amer. J. Physiol.
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1942
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Supplemental
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Soskin et al
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The Influence of Epinephrine Upon the Exchange of Sugar Between Blood and Muscle
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Amer. J. Physiol.
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1933
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Supplemental
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Thurs Feb 28
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Krogh
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THE NUMBER AND DISTRIBUTION OF CAPILLARIES IN MUSCLES WITH CALCULATIONS OF THE OXYGEN PRESSURE HEAD NECESSARY FOR SUPPLYING THE TISSUE.
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J Physiology
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1919
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Crone
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The Permeability of Capillaries in Various Organs
as Determined by Use of the (Indicator Diffusion’ Method
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Acta Physiol Scand
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1963
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March 7
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Abramowitz and Stegun
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Table of Laplace Transforms
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see pages 1020-1022
(navigate the book with the links to pages in the left column)
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Homework #4
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Sokoloff
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Excerpt from Sokoloff chapter in Phelps
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Tuesday, April 2
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Godfrey
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Chapter 1: Introduction to Compartmental Modeling
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Compartmental Models and Their Application
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1983
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Homework #5
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Godfrey
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Chapter 2: The Dynamics of Linear, Time-invariant Systems
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Compartmental Models and Their Application
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1983
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Thursday, April 11
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Patlak et al.
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Graphical Evaluations of Blood-to-Brain Transfer Constants from Multiple-Time Uptake Data
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Journal of Cerebral Blood Flow and Metabolism
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1983
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Patlak et al.
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Graphical Evaluation of Blood-to-Brain Transfer Constants from Multiple-Time Uptake Data. Generalizations
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Journal of Cerebral Blood Flow and Metabolism
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1985
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Sokoloff et al.
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The 14C-deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat
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Journal of Neurochemistry
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1977
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FDG
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Carson et al
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Comparison of Bolus and Infusion Methods for Receptor Quantitation: Application to 18-F-Cyclofoxy and Positron Emission Tomography
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JCBF
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1993
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look at the appendices. A: when is graphical analysis linear, B: How to calculate response to Bolus + Infusion
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Logan et al.
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Graphical Analysis of Reversible Radioligand Binding from Time-Activity Measurements Applied to N-c -methyl-( -)-Cocaine PET Studies in Human Subjects
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JCBF
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1990
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Logan
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A review of graphical methods for tracer studies and strategies to reduce bias
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Nuc med Biol
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2003
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Slifstein and Laruelle
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Effects of Statistical Noise on Graphic Analysis ofPET Neuroreceptor Studies
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JNM
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2000
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Homework 6 - final project
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