ENAS 880...Imaging Drugs in the Brain

Fall 2012

Draft Syllabus

DATE

room

SESSION

TOPIC

ARTICLES

SLIDES**

INSTRUCTOR

4-Sep

BCMM 101

1

introduction to PET and neuroreceptor imaging

Fowler 2007

physics

biochem

endpoint

Morris

11-Sep

BCMM 101

2

imaging dopamine receptors, drugs

Wagner 1983

Farde 1986

discuss Fowler

Morris

18-Sep

TAC N207

3

imaging dopamine changes (displacement)

Fisher 1995

Morris 1995

Koepp 1998

evan's notes

Morris

25-Sep

TAC N207

4

smoking/imaging nicotinic receptors

Cosgrove 2009

Brody 2011

Cosgrove

2-Oct

TAC N207

5

equilibrium vs bolus designs

Carson 2000

Marenco 2004

Watabe 2000

Morris

9-Oct

TAC N207

6

smoking/dopamine study comparison

Brody 2004

Barrett 2004

Scott 2007

Cosg/Morris

16-Oct

TAC N207

7

alcohol induced dopamine

Yoder 2009

Urban 2010

Boileau 2003

Cosg/Morris

23-Oct

TAC N207

8

animal models of drug use

Lefoll 2009

Morgan 2002

TBA

Cosgrove

30-Oct

TAC N213

9

SANDY

6-Nov

TAC N107

10

alccoholism/opioid receptors/NTX occupancy

Weerts 2008

Krishnan-Sarin 2007

Weerts 2011

Morris

13-Nov

TAC N107*

11

fMRI basics/comparison to PET

Clare 2009

Poldrack 2009

Wager 2008

Buxton excerpt

Poldrack excerpt

Morris

14-Nov

801 Howard Ave

class vist to PET Center - observe smoking study

injection scheduled for 9:30am

20-Nov

BREAK

27-Nov

TAC N107*

12

fMRI applications-compare to PET

Wang 2001

Stice 2008

Burger review 2011

Carnell review 2012

Cosgr/Morris

4-Dec

TAC N107*

13

imaging schizophrenia

Farde 1992

Tauscher 2002

Meltzer review '08

Urban review 2010

Williams

10-Dec

TAC N205 11am

14

Dopamine movies of Cigarette smoking

Morris 2005

(Morris 2008)

Morris 2013 (restricted)

Normandin 2012

Cosgr/Morris

* lets continue to meet in TAC 2nd floor and hope for an open room