|
|
|
Imaging Drugs in the Brain |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
ENAS 880 /INP 523 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Draft Syllabus -- Fall 2016 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
DATE |
room |
Lect |
TOPIC |
|
ARTICLES |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
8-Sep |
SHM-I304 |
1 |
introduction to Imaging:PET |
Morris |
Morris,Lucas,Cosgrove |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
15-Sep |
SHM-I304 |
2 |
introduction to Imaging:fMRI |
Hampson |
Bennett 2009 |
Eklund 2016 |
Martz 2016 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
22-Sep |
SHM-I304 |
3 |
METHODS 1: imaging receptors,
drugs + Intro to Neurobiology |
Morris, Cosgrove |
Wagner 1983 |
Farde 1986 |
Volkow 2015 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
29-Sep |
SHM-I304 |
4 |
METHODS 2: imaging dopamine
changes (displacement) |
Morris |
|
Morris 1995 |
Koepp 1998 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
6-Oct |
SHM-I304 |
5 |
Applications 1: |
Cosgrove, Hamspon |
Morgan 2002 |
Martinez, 2011 |
Brewer 2008 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
13-Oct |
SHM-I304 |
6 |
METHODS 3: Functional
connectivity |
Hampson |
Fox+Raichle 2007 |
Carhart 2016 |
Wang 2014 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
20-Oct |
|
7 |
Break |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
27-Oct |
SHM-I304 |
8 |
DESIGN-a-THON #1 |
all |
Krishnan-Sarin 2007 |
Weerts 2008 |
Kim 2013 |
|
Koretsky 2012 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3-Nov |
SHM-I304 |
9 |
METHODS 4: equilibrium vs bolus
and Vt vs BP |
Morris, Cosgrove |
Sandiego 2013 |
Sullivan 2013 |
Carson 2000 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
10-Nov |
SHM-I304 |
10 |
Applications 4: expectations,
negative prediction error |
Morris, Cosgrove |
Yoder 2009 |
Urban 2010 |
Boileau 2003 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
17-Nov |
SHM-I304 |
11 |
DESIGN-a-THON #2 |
all |
Oberlin 2013 |
Kareken 2013 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
24-Nov |
SHM-I304 |
|
Break |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
1-Dec |
SHM-I304 |
12 |
APPLICATION 3: smoking/dopamine
study comparison |
Morris, Cosgrove |
Brody 2004 |
Barrett 2004 |
Wing 2015 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
& Brody 2006 (?) |
|
fallypride |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
8-Dec |
SHM-I304 |
13 |
MOVIE REVIEW, PRESS RELEASE: sex
differences, smoking |
all |
Morris
2013 |
Cosgrove 2014 |
Hampson 2012 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
15-Dec |
|
|
final assignment description |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
16-Dec |
TAC N205 |
14 |
|
extras(?) |
Cosgrove 2009 |
Brody 2011 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
KEY: |
|
|
means "tentative" |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
means: no synopsis required - should read quickly |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
means: no synopsis required but MUST READ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
means : watch this video and write an entertaining movie review |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
means: write a snappy press release |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|