| ENAS 880...Imaging Drugs in the Brain |
Fall 2015 |
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Syllabus in Progres |
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KEY: |
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means "tentative" |
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means: skim whole
paper and write 2 questions |
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means: no synopsis required - specific sections to
be read |
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means: no synopsis required but MUST READ |
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means : watch this video and write
an entertaining movie review |
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means: write a snappy press release |
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| DATE |
room |
Lect |
TOPIC |
ARTICLES |
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Supporting docs |
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INSTRUCTOR(s) |
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| 8-Sep |
SHM I 304 |
1 |
introduction to PET (and fMRI)
and neuroreceptor imaging AND BASIC NEUROCHEM |
Morris,Lucas,Cosgrove |
Reward
Circuitry |
Poldrack |
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Morris/Hampson/Cosgrove |
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� |
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| 15-Sep |
SHM I 304 |
2 |
PET METHODS 1: imaging dopamine receptors, drugs |
Wagner
1983 |
Farde
1986 |
Koob
& Volkow 2010 |
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Morris |
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| 22-Sep |
SHM I 304 |
3 |
fMRI METHODS 1: fMRI
basics/comparison to PET |
Bennett
2009 |
Shaywitz
2005 |
Biswal
1995 |
Poldrack |
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Hampson/Cosgrove |
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| 29-Sep |
SHM I 304 |
4 |
PET METHODS 2: imaging dopamine
changes (displacement) |
Logan
1991 |
Morris
1995 |
Koepp
1998 |
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Fisher
1995 |
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Morris |
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| Early October |
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individual feedback on class
participation and synopses |
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| 6-Oct |
TAC N205 |
5 |
PET METHODS 3: equilibrium vs
bolus designs / DESIGN-A-THON ? |
Carson
2000 |
Sullivan
et al 2013 |
Sandiego
et al 2013 |
Morris,Lucas,Cosgrove |
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Kreisl 2010 |
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Morris |
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(review pgs 113-118) |
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| 13-Oct |
SHM I 304 |
6 |
PET METHODS 4: neuroinflammation |
Sandiego
2015 |
Owen
20101 |
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Cosgrove |
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| 20-Oct |
SHM I 116 |
7 |
fMRI METHODS 2: Functional
connectivity |
Hampson
2006 |
Wang
2014 |
Krishnan-Sarin
2007 |
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Fox+Raichle
2007 |
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Hampson/M/C |
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(NOTE ROOM CHANGE) |
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will use for mini design-a-thon |
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| 27-Oct |
SHM I 304 |
8 |
APPLICATION 1: alcohol induced
dopamine (prediction error) DESIGN-A-THON |
Yoder
2009 |
Urban
2010 |
Kareken
et al, 2010 |
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Morris/C/H |
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| 3-Nov |
SHM I 304 |
9 |
APPLICATION 2: smoking/imaging
nic receptors w SPECT, (sex diffs) |
Cosgrove
2009 |
Brody
2011 |
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M/Cosgrove/H |
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| 10-Nov |
SHM I 304 |
10 |
APPLICATION 3: smoking/dopamine
study comparison -- In Class Team Quiz |
Brody
2004 |
Barrett
2004 |
Li
et al 2012 |
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Lucas
2013 |
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M/C/H |
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| 17-Nov |
SHM I 304 |
11 |
MOVIE
REVIEWS(2), PRESS RELEASE: sex differences, smoking |
Morris 2013 |
Cosgrove
2014 |
Hampson
2012 |
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M/C/H |
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moview
review assignment description |
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M/C/H |
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| 24-Nov |
� |
12 |
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Hampson |
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| Final |
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*** |
Final assignment: choose
an imaging paper you like. One we did not read. Write a synopsis. Then write a nice 1-2
page argument for why we should add it to the
syllabus. |
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Hampson/Morris/Cosgrove |
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Due by end of finals week. |
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You are the movie reviewer! |
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You are the press agent! |
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KEY: |
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means "tentative" |
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|
means:
skim whole paper and write 2 questions |
|
|
|
| |
|
|
means: no
synopsis required - specific sections to be read |
|
| |
|
|
means: no synopsis required but MUST READ |
|
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| |
|
|
means : watch this video and write an entertaining movie
review |
|
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| |
|
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means: write a snappy press release |
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Removed Lectures |
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short-lived dopamine release/smoking |
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obesity fMRI v PET |
Wang
2000 |
Stice,
2008 |
Cosgrove ? |
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Wang,Volkow
2008 |
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additional obesity paper |
Eisenstein 2013 |
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basics of fMRI |
Clare
2009 |
Poldrack
2009 |
Buxton |
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supplementary
material |
Ernst
1999 |
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conectivity |
Hong
2009 |
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1.
PAR-12-267 |
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2.
FDA/CTP priorities |
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