Difference between revisions of "BME faculty Senior Projects List 2014"

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== Lab Descriptions ==
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'''Humphrey – Vascular Mechanics and Mechanobiology Lab''' (Biomechanics Track) Our focus is on (i) developing computational models for understanding vascular disease progression and designing clinical interventions, (ii) using genetic, pharmacologic, and surgical models to elucidate mechanisms that underlie diverse vascular conditions, and (iii) using tissue engineered constructs to test hypotheses of mechanosensing and mechanoregulation of extracellular matrix.
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== Project Descriptions ==
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Humphrey '''Quantitative Histology''' – we use histology and immunohistology to quantify regional variations in the distributions of vascular cell phenotype, extracellular matrix, proteases, and cytokines to correlate with computational predictions. Primary focus – image analysis and histopathology.
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'''Computational Hemodynamics''' – working with colleagues in our medical school, we use patient-specific computational models to study vascular disease mechanisms and their treatment. Primary focus - to use image reconstruction methods to create large scale computational models.
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'''Mechanobiological''' Assessments using Cell / Tissue Culture – we subject cultured cells and tissue engineered constructs to well defined mechanical stimuli and assess their mechanobiological responses. Primary focus – cell and tissue culture methods.
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'''Computer-aided Experimentation''' – we use custom computer-controlled devices to perform theoretically motivated experiments. Primary goal – to design, build, and test new testing systems.
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Revision as of 18:20, 12 January 2014

BME Faculty Senior Project Page

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Lab Descriptions

Humphrey – Vascular Mechanics and Mechanobiology Lab (Biomechanics Track) Our focus is on (i) developing computational models for understanding vascular disease progression and designing clinical interventions, (ii) using genetic, pharmacologic, and surgical models to elucidate mechanisms that underlie diverse vascular conditions, and (iii) using tissue engineered constructs to test hypotheses of mechanosensing and mechanoregulation of extracellular matrix.


Project Descriptions

Humphrey Quantitative Histology – we use histology and immunohistology to quantify regional variations in the distributions of vascular cell phenotype, extracellular matrix, proteases, and cytokines to correlate with computational predictions. Primary focus – image analysis and histopathology.

Computational Hemodynamics – working with colleagues in our medical school, we use patient-specific computational models to study vascular disease mechanisms and their treatment. Primary focus - to use image reconstruction methods to create large scale computational models.

Mechanobiological Assessments using Cell / Tissue Culture – we subject cultured cells and tissue engineered constructs to well defined mechanical stimuli and assess their mechanobiological responses. Primary focus – cell and tissue culture methods.

Computer-aided Experimentation – we use custom computer-controlled devices to perform theoretically motivated experiments. Primary goal – to design, build, and test new testing systems.


Faculty Member
 Lab Description Track Location Project title Project title Project title Project title
Humphrey, Jay Vascular Mechanics and Mechanobiology Lab Biomechanics Malone Quantitative Histology Computational Hemodynamics Mechanobiological Assessments using Cell / Tissue Culture Computer-aided Experimentation
Morris, Evan Neuroimaging of Addiction and Medications Development Imaging PET Center, LMP (Medical Campus) Modeling Dopamine Response to Smoking Cigarettes Action of Naltrexone to treat alcoholism Imaging Opioid Receptors in Mood Disorders Imaging a human model of fatigue
Duncan, Jim






Carson, Rich






Saltzman, Mark






Liu, Chi






Constable, Todd






Staib, Larry






































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